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DISRUPT

ON-CHIP TOMOGRAPHIC MICROSCOPY: A paradigm shift for revolutionizing LAB-ON-A-CHIP bioimaging technology

DISRUPT aims to revolutionise biomedical imaging by developing a pioneering technology: integrated tomographic microscopy. This innovative technique combines on-chip tomography and wireless photonics, together with microfluidics and artificial intelligence (AI).

The project aims to leverage CMOS compatibility to create more affordable and compact tomographic microscopes. It aims to demonstrate its potential in applications such as cancer detection and the identification of infected cells, leveraging key advantages in resolution, sensitivity, performance and energy efficiency.

The foundation of DISRUPT is based on CMOS compatibility, a paradigm shift that will enable the development of tomographic microscopes that are more accessible, lighter and more compact compared to current solutions. This innovative approach not only represents a technological improvement, but also has the potential to transform the accessibility and economic viability of advanced biomedical imaging.

DISRUPT’s proposed device not only aspires to be a technological innovation, but is also projected as a tangible solution for various biomedical applications. From early cancer diagnosis to cell characterisation, cancer and infectious disease research, immunocyte phenotyping, stem cell multipotency identification, tissue pathology, haematopathology and infected cell analysis, the range of possibilities is wide and promising.

The intrinsic characteristics of this technology, such as its mass production capability, compactness, low cost, mechanical robustness and energy efficiency, position it as a driver of innovation for future developments in multiple biomedical application fields. Furthermore, it is envisioned as a valuable alternative tool that addresses emerging needs for microscopic analysis and diagnosis in low-resource settings, telemedicine and point-of-care applications. This approach, with potentially enormous societal impact, has the potential to promote early diagnosis of cancer and other diseases and infections, transforming healthcare delivery and democratising access to advanced technologies in the biomedical field.

Funding Entity

Comisión de las Comunidades Europeas

Years

2023-2025

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